Complete Cell Salt Formula for Daily Mineral Support
Supports energy, restful sleep, immune health, and nervous system balance
Traditionally used to support nutrient absorption and mineral balance
More than 15 times the product of our standard bottle
Extended Use and Greater Savings
The extra-large 400g (0.9 lb) Bio28 jar is ideal for families, frequent users, clinics, or anyone who wants to stock up while maintaining a consistent wellness routine.
This larger format contains more than 15 times the product of our
standard Bio28 bottle
,
providing greater value and reducing the need for frequent reordering.
Key Benefits
Supports Mineral and Cellular Balance
Bio28 combines all 12 traditional tissue cell salts in one convenient formula to support mineral balance and the body’s natural restorative processes.
Traditionally Used During Colds, Headaches, and Nervous Tension
This combination has traditionally been used during periods of fatigue, recurring colds, occasional headaches, anxiousness, or nervous tension.
Supports Energy, Digestion, and Everyday Recovery
The complete 12-salt blend is designed to support energy, digestion, nutrient utilization, and general wellness during periods of physical or emotional stress.
Convenient Extra-Large Format
The 400g jar is well suited for households, clinics, frequent users, and anyone who prefers to keep a long-term supply available.
100% Money-Back Guarantee
If you are not fully satisfied with your purchase, contact us and we will help make things right or assist you in finding a product better suited to your needs.
What Are Tissue Cell Salts?
Tissue cell salts are micro-mineral preparations traditionally used in homeopathy to support healthy cell function and mineral balance. Each of the 12 salts has a different traditional role, including support for digestion, immunity, muscles, bones, skin, and the nervous system.
Bio28 combines all 12 traditional cell salts in one easy-to-take formula.
This provides broad support during periods of stress, fatigue, illness, recovery, or increased wellness needs.
Why Take All 12 Cell Salts?
Combining all 12 salts offers a comprehensive approach to everyday mineral support. This blend has traditionally been used to support nutrient absorption, hydration balance, energy, resilience, and the body’s natural restorative processes.
How Bio28 May Support Your Daily Routine
Bio28 may be a helpful addition to your wellness routine when you feel:
Worn out or low on energy
More prone to occasional colds, headaches, or body discomfort
Tense, restless, or emotionally drained
Affected by sluggish digestion or restless sleep
In need of additional support during stressful or demanding periods
Bio28 provides gentle, non-habit-forming support for everyday resilience, emotional balance, restful sleep, and general well-being.
Why Choose Extra-Large Bio28?
Contains all 12 traditional tissue cell salts
Extra-large 400g / 0.9 lb family-size jar
More than 15 times the product of the standard bottle
Supports energy, immune health, and nervous system balance
Traditionally used to support nutrient absorption
Reduces the need for frequent reordering
Backed by our 100% money-back guarantee
Months of Convenient Cell Salt Support
The extra-large format provides a cost-effective way to maintain your routine without frequent reordering. It is ideal for busy households, frequent users, and anyone who prefers to stock up and save.
Active Ingredients
Calc Fluor 6X, Calc Phos 6X, Calc Sulph 6X, Ferr Phos 6X, Kali Mur 6X, Kali Phos 6X, Kali Sulph 6X, Mag Phos 6X, Nat Mur 6X, Nat Phos 6X, Nat Sulph 6X, and Silicea 6X.
Directions for Best Results
Take with water 3–4 times daily, or use as directed.
Ages 12 and older: 5 pellets
Ages 3–11: 3 pellets
Children under age 3: Consult a doctor before use
Product Information
Form: Homeopathic pellets Size: 400g / 0.9 lb Supply: May provide more than a one-year supply when used as recommended, depending on individual frequency of use
Inactive Ingredients
Lactose and Magnesium Stearate.
Explore our complete collection of Cell Salt remedies.
This product contains lactose. Consult your doctor or qualified healthcare provider before use if you have health concerns, are pregnant or nursing, are taking prescription medication, or are considering use for a young child.
The information provided on our website is for general health and wellness purposes and is not a substitute for professional medical advice. Always consult your doctor or qualified healthcare provider regarding health concerns, and carefully read all product directions before use.
*Claims are based on traditional homeopathic practice and are not accepted medical evidence. These statements have not been evaluated by the Food and Drug Administration.
100% MONEY-BACK GUARANTEE
All of our products come with a 100% Guarantee.
If you are unhappy for any reason and we do not resolve it,
we will refund 100% of the original purchase price.
Our goal is to help you, so we proudly stand behind our products.
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Total Tissue Cell Salt Mineral Combination BIO28
Helps Your Body Absorb and Use Nutrients, Increases Energy Levels, Helps Improve Sleep Patterns, Overall Health and Vitality
I can't really tell what it's doing, but I do feel happier and healthier; my sleep seems better, too.
My stools are kind of green, but they say it's normal as your body adjusts to the salts.
Store owner replied:
From toddlers to adults, the whole family covered! That's the best kind of staple to have at home. Thank you, Olivia 💚
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
With being a salty person, Cell Salts brighten me up, instill discipline by having to take them 3 times a day and also curb my sugar cravings⚡️🙏🏼⚡️
Store owner replied:
Cell salts and discipline in one little pellet, we'll take that! So glad they're working for you, Max ⚡
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Have not been taking long. But they are easy to take and so far I feel great!
Store owner replied:
Yaay! We hope it keeps going well! 🌻
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
The tissue salts are awesome! It's easier and quicker than taking out the 12 tissue salts 6x individually. If you're taking all 12 of the tissue salts, this combination salts makes life easier.
Store owner replied:
You nailed it, Lilawatee! That's exactly why BIO28 exists. Thank you for sharing that! 🌸
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Store owner replied:
Long time customers like you mean everything to us, Pamela. ✨ Thank you for sticking with us! 🌸
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Makes me feel so much more energized and ready to tackle life!
Store owner replied:
Ready to tackle life. That is the goal! 🤩 Love hearing this, Sarah. Keep it up!
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Store owner replied:
Great start, Kaleigh! It only gets better from here. Thank you! 🥰
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
I have used these products for years. Now discovering them at BestMade Natural Products. They Work!
Store owner replied:
A cell salt veteran finding a new home at Bestmade, we love that! 🤩Welcome, Vera. So happy you found us! 💚
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Literally LIFE CHANGING!! The total tissue cell salt completely HEALED my eczema!! I had been suffering for almost a year and had tried EVERYTHING to no avail. I was barely sleeping and had no life bc of how bad it was. I knew about cell salts but honestly wasn't sure they would really help. Boy was I wrong!! I'm so incredibly thankful I was recommended to take Bestmade! I now reach for these salts for everything and will never look back! So grateful for yall!!
Store owner replied:
Chelsey, seeing that photo and knowing where you are now... wow 🥹 So incredibly happy for you. Thank you for trusting us and for sharing this 💚
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Easier to take than the individual bottles.. more convenient..
Store owner replied:
David, convenience makes it so much easier to stay consistent. Glad that format is working better for you 🥰
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Store owner replied:
Short and to the point, Peter, we’ll take it 😄
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
I have ridiculous food allergies...actually brain allergies. The only thing that helps when I get dosed are all 12 cell salts. I used to use NuAge Bioplasma...worked great! Then Hylands bought them out to close them down. Hylands Bioplasma sucks. The formula is all wrong. I found a brand from Canada...pretty good but based in sugar.. kind of slow to dissolve. Finding you is a God send!
Store owner replied:
Ira, you’ve clearly tried everything out there 😄
Really glad you landed on something that actually feels right for you. That’s not always easy to find 🌻
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Store owner replied:
It means a lot to hear that, Christy. Thanks for taking a moment to share your experience 🤩
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
I just started taking this product faithfully along with my other wellness program! I love this product
Store owner replied:
Darian, I love that. That kind of consistency is great! Glad it’s off to a good start for you 🥰
Warmly,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Store owner replied:
Oh wow that’s a statement 😆 Appreciate you saying it straight like that 💚
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
This order came within days, super fast delivery which is exceptional. A co-worker & I are splitting the product. I can't say I have noticed any difference as of yet but look forward to seeing any changes for the better.
Store owner replied:
We’re glad your order arrived quickly, Shannon. Hopefully, as you continue using it, you’ll start noticing positive changes 😃
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
Order delivered on time in great shape. I take them 3 times a day. So far not notivced too much difference as yet.
Store owner replied:
Good to hear everything arrived safely, Josephine. Hopefully, with a bit more time, you’ll start to notice how it’s working for you 🤞🏼☺️
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
just started taking it and I feel a lot better, sleeping better
Store owner replied:
So glad to hear you’re already feeling better and sleeping more soundly, Frances. Thanks for sharing your early experience 🥰
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
Recently received. Looking forward to experiencing the Benefits
Store owner replied:
Thanks for sharing, Lisa 🥰 We hope you notice the benefits as you continue using it, and we’re glad it made its way to you safely 💚
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
We take this daily so I’m excited to have a bigger size option!
Store owner replied:
Candace, it’s great to hear this is already part of your daily routine. We’re happy the larger size fits your needs better 😍
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
I have just started to use these cell salts and hope that they will help me to stay healthy. It was a good price point and will last me a long time.
Store owner replied:
Susan, thank you for sharing where you’re starting from. We’re glad the size and price point felt right for you and hope it supports your long term wellness goals 🌻
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
Love these cell salts. I use the box for healing my family and animals! We just started using the total in one now. I’m excited to see the results. We love these products as an entire farm♥️♥️
Outstanding quality and value. I can feel a real difference between these and other formulas like it. I will never use another brand again. Thank you for making these and for setting the bar so high.
Store owner replied:
Claudia, it means a lot to hear you can genuinely feel the difference compared to other formulas you’ve tried 🥰
Setting a high standard is something we take seriously, and your experience tells us we’re doing that right 💚
Warmly,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
I use a scale that provides water % and until I started using these cell salt minerals, I’ve never been able to increase my hydration above 44%, and now I’m just over 46%, which is excellent!
Store owner replied:
That’s honestly so cool, Terri! Seeing an actual change like that on your scale must feel really validating. Thanks for sharing such a specific (and fascinating!) result, we love hearing how people track their progress 💧 💚
Warm hugs,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
Take these daily and really like how well they worked!
Store owner replied:
That’s amazing to hear, Sheree! We love that BIO28 has become part of your daily routine and that you’re feeling the benefits. Thanks for being with us 🥰
Warm hugs,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
So far so good. They are easy and convenient to take and I feel like they are helping fill in the gaps that might be missed between other supplements and food based nutrients. I like the fact that they are broad spectrum and will address any/all deficiencies without side effects.
Store owner replied:
That’s really great to hear, Jack! 😊
Feeling calmer and more balanced can make such a difference day-to-day. Thanks for sharing your experience, we’re happy it’s helping you.
Warm hugs,
Giovanna
Customer Care Team | BestMade Natural Products 🌿
I am familiar with these salts as I have purchased Schuessler salts every time I have gone to Germany over the past decades. It is nice to know that I can now buy this combination in the US.
Store owner replied:
It's amazing how complementary these remedies are, Debi! We are so delighted to hear the Cell Salts are amplifying that wonderful feeling of engagement. It's truly a joy to read this! 🤩
Warm hugs,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Being Canadian and on disability this was a very expensive purchase for me. I have cptsd and insomnia, no bullshit I felt the change within the second day. I was able to get myself off half my pharmecuticals for cptsd ( poison)
Since taking the cell salts my nervous system has settled, first time in 5 years, my body feels clean and noticed a huge difference in mental clarity and have been able to accomplish so much more of my daily have to do's. I bought a 2 month supply and unfortunately wont be able to buy again due to Canadian dollar is USA. I have full confidence I will be able to get off all pharmaceuticals within the next 2 months. I totally stand by this product just wish you had a company on Canada. Woot! Woot! For cell salts, has changed my life.
Store owner replied:
Laura… your review genuinely touched us.
Hearing that your system finally settled after everything you’ve been through, that’s huge, and we’re so glad the salts gave you that kind of relief. 💛
And about the Canada–USD struggle… we feel you. If we could pop up a little Bestmade Canada warehouse, trust me, we’d be cutting the ribbon tomorrow. 🇨🇦
Just so you know, we do have a big holiday promo running right now, and it’s the best pricing we offer all year. No pressure at all, just wanted to share in case it helps make things a bit lighter for you.
We’re cheering for you every step of the way. Woot woot right back at you. 💛
Warm hugs,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
Its changed everything!
Since chemo & radiation 20+ yrs ago, Ive struggled with concistant bowel movements.
Also, I've been getting dizzy/disoriented as I work throughout the day.
This product has been Amazing.
All issues solved..! & I feel stronger everyday. Im THRILLED to recommend this product!
Store owner replied:
Teri… this one stopped us in our tracks.
After everything your body’s been through, hearing that you’re feeling stronger and steady again? That’s massive 🥳
Thank you for trusting us and for sharing something so meaningful. 💛
Warm hugs,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
I have only been taking them for a couple of weeks now. Haven’t noticed anything but it hasn’t been that long. Not sure why you want a review for a supplement so early.
Store owner replied:
Fair point, Brent. We may have jumped the gun a little by asking for a review 🫣
Thanks for the honesty.
Give it a bit more time, and we’ll be here rooting for a good update. 🙌
Warm hugs,
Giovanna
Customer Care Team | Bestmade Natural Products 🌿
